Endocrine Abstracts

Subclinical hypothyroidism (SCH) is a common disorder and indications of treatment are still being debated. The aim of our study was to describe the therapeutic and evolutionary characteristics of SCH.Methods: We undertook a longitudinal retrospective study in 110 patients with SCH biologically defined by increased serum thyroid-stimulating hormone (TSH) levels (>4 mIU/l) and normal FT4. Pregnancy, age less than 18 years, personal history of partial ...

Introduction: The syndrome of resistance to thyroid hormone is a rare inherited disorder characterized by elevated circulating thyroid hormones, failure to suppress pituitary thyroid stimulating hormone (TSH) and variable tissue target hyposensitivity to thyroid hormone action. We reported the case of a RTH syndrome with a novel mutation.Case report: A 15-year-old girl was investigated for visual hallucinations and behavior disorders. Her medical history...

Introduction: Secondary high blood pressure is commonly diagnosed in young patients. In recent years, hypertension is increasing as well as the other components of metabolic syndrome such as obesity. The aim of this study was to determine the etiology of hypertension in patients aged <40 years old admitted in an endocrinology department.Materials and methods: It was a retrospective study including 55 patients <40 years old hospitalized at the end...

Introduction: Hypoglycemia is an uncommon complaint among non diabetic patients. The aim of this study was to determine the role of fast test in the diagnostic approach to hypoglycemia.Patients and methods: It was a retrospective study, including 40 patients admitted in the endocrinology department from 2001 to 2015 for hypoglycemia signs. We collected clinical and biologic data, fast test results and final diagnosis of hypoglycemia.<p class="abstext...

Introduction: Atrial fibrillation (AF) occurs in up to 15% of patients with hyperthyroidism. Although hyperthyroidism is usually regarded as a reversible cause of AF, spontaneous sinus conversion occurs in only 2/3 of patients upon the normalization of T4 levels. The aim of this study was to identify factors associated with persistent atrial fibrillation after restoration of euthyroid state.Methods: We conducted a retrospective study of 13 years. Twenty ...

Bakground: Thyroid-lobectomy is a frequent procedure performed in patients with a variety of thyroid conditions.The aim of this study is to determine the prevalence of post-operative hypothyroidism and the risk factors of hypothyroidism in patients undergoing thyroid-lobectomy.Patients and methods: We retrospectively reviewed patients who underwent a thyroid lobectomy for benign disease from january 2000 to 2014. Patients with known hypothyroidism before...

Introduction: Hypopituitarism is a known cause of bone mineral loss. Our study aimed to evaluate the frequency of osteopenia and osteoporosis in patients with Sheehan’s syndrome and to evaluate its management.Subjects and methods: It is a retrospective longitudinal study concerning 60 cases of Sheehan’s syndrome that have had a bone mineral density measurement. The parameters of osteodensitometry, the received treatment and the follow up data w...

Introduction: Cardiovascular complications are well known in type 2 diabetes with other factors of cardiovascular disease. Recently, with the intensive treatment of type 1 diabetes, many studies have focused on macrovascular complications in type 1 diabetes. The aim of our study was to determine the long-term cardiovascular risk factors and macrovascular complications in type 1 diabetic patients.Patients and methods: A retrospective study involving 45 pa...

Introduction: Steroid 11β-hydroxylase deficiency (11-OHD) is the second most common causeof congenital adrenal hyperplasia (CAH),characterized by the overproduction of adrenal androgens and deoxycorticosterone (DOC).It usually presents with virilization of the female fetus, precocious puberty in male infants and hypertension with or without hypokalemia in both genders. Because of high levels of mineralocorticoids, patients rarely present with salt wasting (SW). We herein ...

Introduction: Severe hypercalcemia is a life-threatening condition which should be managed urgently. Its pharmacological treatment consists of intravenous saline hydration, loop diuretic and intravenous administration of bisphosphonates. However, data evaluating these treatments are very limited.The aim of this study was to assess the efficiency of saline hydration, furosemide, and bisphosphonates in the management of severe hypercalcemia secondary to a ...